Antonia Göhler - NanO Postdoc

Antonia

I have just started working in the Davis lab as a post-doc. I will develop a new, upright super- resolution imaging system for use in integrative neuroscience experiments in collaboration with the Micron and Nano team.

Before coming overseas, I finished my PhD thesis in Markus Sauers Lab in Wuerzburg (Germany). During my time in the Sauer Lab I gained a strong knowledge of confocal (FCS, Fluorescence Correlation Spectroscopy) and widefield setup construction, high-resolution techniques especially dSTORM and data analysis. I studied hydrodynamic behaviour of glycoproteins as well as their spatial distribution on cell surfaces and the overall distribution of sugar molecules on the cell surface.

Here I will get new insights into a different field of biology. The project will be absolutely interdisciplinary bringing together microscope building and novel biological applications.

 

Publications

2013

  • M. Dietz, D. Haße, D. M. Ferraris, A. Göhler, H. H. Niemann, M. Heilemann, Single-molecule photobleaching reveals MET receptor dimerization upon ligand binding in intact cells. BMC Biophysics, 6:6, 2013
  • J. Seibel, S. König, A. Göhler, S.Doose, E.Memmel, N. Bertleff, M. Sauer. Investigating infection processes with a workflow from organic chemistry to biophysics: the combination of metabolic glycoengineering, super-resolution fluorescence imaging and proteomics. Expert Rev. Proteomics, 10(1): 25-31, 2013.

2012

  • A. Göhler, C. Büchner, S. Andre, S. Doose, H. Kaltner, and H.-J. Gabius. Analysis of homodimeric avian and human galectins by two methods based on fluorescence spectroscopy: Different structural alterations upon oxidation and ligand binding. Biochimie, 94(12): 2649-2655, 2012.

2011

  • A. Göhler, C. Büchner, S. Andre, S. Doose, H. Kaltner, and H.-J. Gabius. Sensing ligand binding to a clinically relevant lectin by tryptophan fluorescence anisotropy. Analyst, 136:5270-5276, 2011.

2010

  • A. Göhler, S. André, H. Kaltner, M. Sauer, H.-J. Gabius, and S. Doose. Hydrodynamic properties of human adhesion/growth-regulatory galectins studied by fluorescence correlation spectroscopy. Biophysical Journal, 98(12):3044-3053, 2010.