Sherratt Lab

Research in the Sherratt group is aimed at understanding how DNA replication, recombination and chromosome segregation shape bacterial chromosome organization in the context of the living cell.

The research observes where genes and molecular machines are positioned as a cell proceeds through its growth and division cycles, and what happens when normal cellular behaviour is perturbed by different methods. Individual components of DNA organizing and processing machines are studied genetically, structurally and biochemically, and information on their molecular action is integrated into the context of their action in cells.

Running FtsK hexamer

Model of FtsK C-terminal domain with hexameric motor (blue) and trimeric gamma-subdomain (yellow) bound to KOPS (red).



Our most recent publications below.

For more listed on PubMed.


Research associate postdocs


Technical staff


Recent former lab members



Enquiries with CV welcome. For postdoc or graduate student positions, please contact Prof. David Sherratt directly.