Alan Wainman - Micron Post-doc

email:alan.wainman@path.ox.ac.uk

Alan

I am a Post-doc in the Dunn School of Pathology where I look after the light microscopes. I'm also a Post-doc in Jordan Raff's lab where I am interested in understanding how a cell can cope with either too few centrosomes or too many.

Publications

2015

  • Conduit PT, Wainman A, Novak ZA, Weil TT, Raff JW. Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP. Elife. 2015 Nov 4;4. pii: e08483.
  • Conduit PT, Wainman A, Raff JW. Centrosome function and assembly in animal cells. Nat Rev Mol Cell Biol. 2015 Oct;16(10):611-24.
  • Richens JH, Barros TP, Lucas EP, Peel N, Pinto DM, Wainman A, Raff JW. The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM. Biol Open. 2015 Jul 8;4(8):1052-61.
  • Janina Baumbach, Zsofia Anna Novak, Jordan W. Raff and Alan Wainman. Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo. PLoS Genetics 11(5): e1005261

2014

    Paul T. Conduit, Jennifer H. Richens, Alan Wainman, James Holder, Catarina C. Vicente, Metta B. Pratt, Carly I. Dix, Zsofia A. Novak, Ian M. Dobbie, Lothar Schermelleh and Jordan W. Raff. A molecular mechanism of mitotic centrosome assembly in Drosophila. eLife

    Zsofia A. Novak, Paul T. Conduit, Alan Wainman, Jordan W. Raff. Asterless Licenses Daughter Centrioles to Duplicate for the First Time in Drosophila Embryos. Current Biology, June 2, 2014. 24, 1-7

  • Paul T. Conduit, Zhe Feng, Jennifer H. Richens, Janina Baumbach, Alan Wainman, Suruchi D. Bakshi, Jeroen Dobbelaere, Steven Johnson, Susan M. Lea, and Jordan W. Raff The Centrosome-Specific Phosphorylation of Cnn by Polo/Plk1 Drives Cnn Scaffold Assembly and Centrosome Maturation. Developmental Cell, 20 March 2014

2012

  • Roque H, Wainman A, Richens J, Kozyrska K, Franz A, Raff JW. Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation. J Cell Sci. 2012 Sep 12.
  • Wainman A, Giansanti MG, Goldberg ML, Gatti M. The Drosophila RZZ complex: roles in membrane traffic and cytokinesis. J Cell Sci. 2012 Jun 8.

2009

  • Wainman A, Buster DW, Duncan T, Metz J, Ma A, Sharp D, Wakefield JG. A new Augmin subunit, Msd1, demonstrates the importance of mitotic spindle-templated microtubule nucleation in the absence of functioning centrosomes. Genes Dev. 2009 Aug 15;23(16):1876-81.
  • Wainman A, Creque J, Williams B, Williams EV, Bonaccorsi S, Gatti M, Goldberg ML. Roles of the Drosophila NudE protein in kinetochore function and centrosome migration. J Cell Sci. 2009 Jun 1;122(Pt 11):1747-58. Epub 2009 May 5.
  • Stevens NR, Dobbelaere J, Wainman A, Gergely F, Raff JW. Ana3 is a conserved protein required for the structural integrity of centrioles and basal bodies. J Cell Biol. 2009 Nov 2;187(3):355-63. Epub 2009 Oct 26.

2008

  • Hughes JR, Meireles AM, Fisher KH, Garcia A, Antrobus PR, Wainman A, Zitzmann N, Deane C, Ohkura H, Wakefield JG. A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol. 2008 Apr 22;6(4):e98.