Dr. Andrew Johnston

 
MSc (Imperial, London)
DPhil (Oxon)


Andrew Johnston is originally from Crosby, Liverpool. In 2008 he began his studies at Imperial College London, graduating with MSci Physics in 2012. The third year of his degree was spent at the Universidad Autónoma de Madrid.  In Madrid, Andrew undertook his MSci project with Prof. José García Solé which involved assessing the suitability of inorganic fluorescent nanoparticles for cancer treatment and diagnosis.  In the summer of 2011 he also spent time in the Pharmacology Department at University College London working with Green Fluorescent Proteins (GFPs) under the supervision of Dr Guy Moss

Andrew's PhD research focuses on understanding the atomic structure of pharmaceuticals in physiologically relevant environments, using a combination of NMR, neutron scattering and computer simulations.

 Andrew joined the group in October 2012.

Publications:

5.  The solvation structure of alprazolam

Accepted, Phys. Chem. Chem. Phys., 18, 22416-22425 (2016)
Sridhar, A, Johnston, AJ, Varathan, L, McLain, SE and Biggin, PC
DOI:10.1039/C6P02645A

4. On the positional and orientational order of water and methanol around indole: a study on the microscopic origin of solubility

Phys. Chem. Chem. Phys., 18, 23006-23016  (2016) Henao, A, Johnston, AJ, Guardia, E, McLain, SE and Pardo, LC
DOI: 10.1039/C6CP02645A

3. On the Atomic Structure of Cocaine in Solution

Phys. Chem. Chem. Phys., 18 991-999 (2016)
Johnston, AJ, Busch, S, Pardo, LC, Callear, SK, Biggin PC & McLain SE
DOI:10.1039/C5CP06090G


2.
Amphipathic Solvation of Indole: Implications for the Role of Tryptophan in Membrane Proteins

J. Phys. Chem. B,
119 (19), 5979-5987 (2015).
Johnston, AJ, Zhang, Y (Rosie), Busch, S, Pardo, LC, Imberti, S & McLain SE
DOI: 10.1021/acs.jpcb.5b02476


1. 
Conformation and interactions of dopamine hydrocholride in solution
J. Chem. Phys. 142, 014502 (2015).

DOI:10.1063/1.4904291
Callear, SJ, Johnston, AJ, McLain, SE and Imberti, S

Presentations:

3. Cracking the structure of cocaine in solution: Determining the atomic structure of cocaine in solution.

American conference on Neutron Scattering, June 2014 (Poster)
Knoxville, Tennessee USA

2. Cracking the structure of cocaine: The atomic structure of pharmaceuticals in solution. 
Red Kite Meeting, January 2013 (Oral presentation)
Physical and Theoretical Chemistry Laboratory, Oxford, UK

1. The structure of indole in solution: Insights from neutron scattering and computer simulation.
International Conference on Neutron Scattering, July 2013 (Poster)
Edinburgh, UK

Contact Details:
email: andrew.johnston@stx.ox.ac.uk
Tel: +44 (0) 1865 613 311

Andrew and Instrument scientist Dr. Silvia Imberti test measured samples for radiation on the SANDALS instrument at ISIS (STFC, UK) - December 2012.
                                                                                                                                           
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